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FluoGuide develops surgical solutions that is expected to reduce suffering for the patient and increases the likelihood of cure as well as reducing costs for the health care system.

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FluoGuide annonces publication of two patent applications covering the company’s uPAR technology platform for improving surgery

Press release


February 2, 2021

Copenhagen, Denmark, 2 February 2021 – FluoGuide A/S (“FluoGuide” or the “Company”) announces that two new patent applications, covering the use of uPAR in enhancing surgical precision by illuminating cancer cells, have been published.

FluoGuide hereby updates on the status of its published patents and patent applications. Since prior to the IPO, FluoGuide holds the patent family (WO2016041558), relating to the Company’s lead compound FG001. FG001 is designed to allow surgeons to clearly delineate cancer from normal tissue during surgery through a novel uPAR-targeted luminescent technology and has demonstrated to be well tolerated and ability to light up cancer in an ongoing phase I/II clinical trial on guiding surgery of high grade glioma. Patents have been issued in Europe, the US, and Australia and expire in 2034.

On July 16 2019, FluoGuide submitted applications on two additional patent families; (PCT/EP2020/069991 and PCT/EP2020/070014), which will be covering relevant selected regions/countries worldwide if granted. The first patent family application (PCT/EP2020/069991), relates to FluoGuide’s second compound, FG002, and covers an uPAR-targeting peptide conjugate with an optimal pharmacokinetic profile intended for administration in a human body. Further, there is provided an uPAR-targeting peptide conjugate and a composition comprising the uPAR-targeting peptide conjugate for use in optical imaging and for diagnosis and/or treatment of a disease. The patent family is licensed from Copenhagen University Hospital (Rigshospitalet) and University of Copenhagen.

The second patent family application (PCT/EP2020/070014), covers a receptor-targeting conjugate with a high receptor binding affinity in combination with an optimal pharmacokinetic profile intended for administration in a human body. The application relates to more uPAR targeted products use to guide surgery. This patent family is owned by FluoGuide.

According to standard patent procedure, applications are made public 18 months after submission. There are no guantees that a patent application will lead to grant of a patent.

“We are following a patent strategy that will ensure the best possible position to utilize uPAR target surgical guidance and the publication of the two patent applications goes in line with this strategy” says Morten Albrechtsen, CEO and continues ”We will continue filing for new patents giving the best protection of our development programs.”